Maria Pires Pacheco

Luxembourg

@mariapirespac

Badges

Python
Sql

Certifications

Work Experience

  • SENIOR BIOINFORMATICIAN AND DATA SCIENTIST

    University of Luxembourg•  January 2019 - Present•  Luxembourg

    Led the Metabolic Unit in Systems Biology, applying data science and machine learning techniques to analyze large-scale patient transcriptomics datasets using R and MATLAB, resulting in actionable insights for targeted treatment strategies. Developed algorithms and metabolic models to predict cancer-specific metabolic pathways and identify potential drug targets, enhancing targeted treatment strategies. Supervised 4 PhD and 9 Master’s students, fostering a collaborative environment and ensuring high standards in research quality.

  • BIOINFORMATICIAN AND DATA SCIENTIST

    •  January 2017 - December 2018

    Designed data pipelines and workflows to analyze gene expression and LC-MS data, for data extraction and transformation related to plant stress modeling. Developed tools for metabolic modeling (FASTCORE) and managed large-scale data integration projects. Applied statistical analysis and machine learning to RNA-seq and single-cell RNASeq data for drug prediction, improving prediction accuracy by 30% and decreasing running time by 6000-fold.

  • Lab technician, high school teacher, pedagogic assistant, consultant

    •  January 2004 - December 2010

Education

  • University of Luxembourg

    PHD IN BIOLOGY (SYSTEMS BIOLOGY)•  January 2012 - December 2016

  • University of Luxembourg

    MASTER INTEGRATED SYSTEM BIOLOGY•  January 2010 - December 2012

  • Université Pierre et Marie Curie

    DEUG, LICENCE, MAITRISE EN BIOLOGIE CELLUAIRE ET PHYSIOLOGIE•  January 1999 - December 2004

Skills

Git
Slack
Teams
Microsoft Office
TensorFlow
Keras
PyTorch
SciKit-Learn
XGBoost
LightGBM
FASTCORE
COBRA toolbox
MATLAB
R
Python
SQL